-Yahoo, etc... knowing I am a male, and so my computer seems half-filled with ads for off-brand dating sites with video loops of 19 year old girls "flirting" with the camera. I'm good, thanks.
-Seeing 17 year old kids walking down the street, heading away from the high school at 9:45 in the morning, who obviously just ducked out of going to school.
-When the cat pees on me when I take him to the vet
-When the government has to bail out financial institutions who behaved obviously recklessly for years to even a nimrod like myself, putting us even further into crippling debt, in order to keep us from having some sort of 1929-style financial collapse.
-The lack of a proper Hawkman title from DC
-Dolls that can swim. And the inferred message to impressionable kids that maybe babies can swim.
-When your trusted robot goes crazy and tries to kill you.
-Daytime TV ads reminding me I'd probably have a full-time job if I DID just sign up for a trade and technical school...
(edit) - I am also deeply irritated that whenever I turn on my cable TV, it tunes to channel 1, which runs nothing but an ad for the three services (cable, internet, phone) provided by Time Warner Cable. Which I already have. Time Warner, please quit selling me (badly and constantly) that which I already have.
Of course, the only way you can actually see the ad is if you already have digital cable, thus eliminating at least one of the three items they're hard selling.